Aging is generally viewed as a slow, timeless process that spreads over time. However, a new scientific study conducted at the molecular level shows that the feeling of age suddenly accelerating when looking in the mirror may not be your imagination.
According to research by Stanford University geneticist Michael Snyder and his team, the human body goes through two sharp turning points over the course of a lifetime. The first major wave of change occurs at the average age of 44, and the second major breakthrough occurs at around the age of 60.
Experts claim that quite dramatic and sudden jumps in human biology occur during these age periods, regardless of the class of molecules considered.
Risks increase suddenly, not gradually
Scientists monitored 108 adults between the ages of 25 and 70 for years to prevent age-related diseases and develop more effective treatments. More than 135,000 biological traits, including RNA, proteins, lipids and body microbiomes, were examined using biological samples taken from participants at regular intervals.
The analysis of billions of data points found that the risk of diseases such as Alzheimer's and cardiovascular disease does not increase slowly over time, but increases sharply beyond these two critical ages. About 81 percent of the molecules studied were observed to undergo radical changes in at least one of these two age periods.
There are many reasons for change
At the first fracture, which occurs around age 44, the changes are most pronounced primarily in molecules related to lipid, caffeine and alcohol metabolism, as well as in skin and muscle tissue. Although researchers predicted that this sudden change in the mid-40s could be related to the process of menopause in women, the data proved that the situation is not limited to just that. Because it was found that men of the same age also suffer similar molecular breaks.
This suggests the existence of more dominant biological factors that affect both sexes. In the second wave, around age 60, there are major changes in vital systems such as carbohydrate metabolism, immune regulation and kidney function.

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